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Time-Restricted eating tested to cut heart risk in childhood cancer survivors

NCT ID NCT07009288

Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 04, 2026 · Updated 3 times

Summary

This study tests whether time-restricted eating (eating only during a set window each day) combined with regular coaching calls can help adult survivors of childhood cancer lose weight and lower their risk for heart disease and diabetes. Three hundred survivors with a BMI of 25 or higher will either follow the eating plan with coaching or receive standard educational materials and monthly weight checks. The goal is to see if this approach leads to meaningful weight loss and better blood sugar levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
time-restricted eating (TRE) plus motivational coaching calls
What this could lead to
If it works, this could offer a simple, drug-free way for childhood cancer survivors to manage weight and reduce their risk of heart disease and diabetes.
What could go wrong
This is a behavioral study, not a drug trial, so results depend on participants sticking to the fasting schedule. It is also early-stage and may not work for everyone or produce lasting changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

May 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Enrolled in the Childhood Cancer Survivor Study (a cohort of 5+ year survivors of childhood cancer diagnosed at age \< 21 between 1970-1999 at 31 participating institutions in North America) * Are ≥18 years old * Self-reported body mass index ≥ 25 kg/m2 * Are not pregnant or do not intend to become pregnant in the next year * Stable weight over the past 3 months (+/- 10 pounds) * If on oral medication for insulin resistance (ie, metformin), elevated blood pressure, or dyslipidemia, medication dose must be stable (ie, unchanged \> 3 months) * Have internet access (can be via smartphone or computer). If neither device is available, the study can loan participants a Wi-Fi enabled device. Exclusion Criteria: * Do not reside in the United States * Do not speak English * Eating window \< 12 hours per 24-hour day * On insulin or GLP-1 agonist * Diagnosis of type 1 diabetes mellitus * Enrolled in a formal weight management program or other weight loss trial * History of an eating disorder

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Childhood cancer survivors

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Fred Hutchinson Cancer Research Center (Data Collection Only)

    NOT_YET_RECRUITING

    Seattle, Washington, 98109, United States

  • Hunter College

    NOT_YET_RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • St. Jude Children's Research Hospital (Data Collection Only)

    RECRUITING

    Memphis, Tennessee, 38105, United States

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