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Could a 14-Hour overnight fast help childhood cancer survivors?

NCT ID NCT03523377

Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study looks at whether not eating for at least 14 hours overnight (a form of intermittent fasting) is practical and can help improve blood sugar levels in adults who survived childhood cancer. Participants are randomly assigned to either follow this fasting schedule with coaching support or stick to standard healthy eating and exercise advice. The goal is to see if this simple lifestyle change can reduce the risk of diabetes and other metabolic problems common in cancer survivors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
prolonged overnight fasting
What this could lead to
If successful, this could offer a simple, drug-free way to improve blood sugar control and reduce long-term health risks in childhood cancer survivors.
What could go wrong
This is a small feasibility study, so results may not apply broadly. Fasting for 14 hours nightly may be hard to maintain, and the impact on health outcomes is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Apr 2018

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Body mass index is ≥ 18.5 kg/m\^2 * History of treatment for cancer or related illness diagnosed at ≤ 25 years old * Off cytotoxic therapy for primary cancer ≥ 2 years * Not receiving cytotoxic therapy (chemotherapy, external beam radiation therapy) at the time of study enrollment * History of radiation to the chest, abdomen or total body * Current age ≥18 years * English-speaking * Personal phone with SMS text messaging capability * Willingness to wear an mHealth device, such as a FitBit, for two 7-day periods * Able to perform all study requirements Exclusion Criteria: * Use of any antidiabetic, weight loss, or appetite control medication * Use of any other medication that could impact dietary intake, such as prednisone * Currently fasts 12 hours or more by self-report * Unable to fast due to medical reason such as pregnancy

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Conditions

The condition(s) this trial relates to.

Fasting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Childhood cancer survivors

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.