Heart bypass patients: how long should you take blood thinners?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients 18-80 of age. 2. Patients undergo planned CABG for the first time with ≥1 SVGs 3. Patients with written informed consent. Exclusion Criteria: 1. Patients undergoing concomitant valve surgery (excluding aortic bioprosthesis), aortic surgery, or rhythm surgery during the same session. 2. Patients undergoing emergency CABG. 3. Patients with single-vessel coronary artery disease. 4. Patients with cardiogenic shock or hemodynamic instability. 5. Patients with sick sinus syndrome, second- or third-degree atrioventricular block. 6. Patients with contraindications for coronary computed tomography angiography (CCTA) or coronary angiography, including contrast media allergy. 7. Patients requiring antiplatelet therapy other than aspirin or ticagrelor (e.g., clopidogrel, prasugrel) and unable to discontinue such medication after CABG, based on physician or investigator judgment. 8. Patients on oral anticoagulants before CABG who must continue anticoagulation therapy postoperatively. 9. Patients with contraindications for ticagrelor or aspirin, including: 9.1Bleeding diathesis within the past 3 months. 9.2Severe gastrointestinal bleeding within the past year. 9.3Peptic ulcer (even without bleeding) within the past 3 years. 9.4History of intracranial hemorrhage, aspirin allergy, or severe aspirin-induced gastrointestinal reaction. 10. Patients with a drug-eluting stent (DES) in a coronary or cerebral artery within 6 months before CABG, or a bare-metal stent (BMS) within 1 month before CABG. 11. Patients with thrombocytopenia (\<100 x 10⁹/L) before CABG. 12. Patients with severe renal dysfunction requiring dialysis or active liver disease, including unexplained persistent transaminase elevation or transaminase levels \>3× the upper normal limit. 13. Patients using strong CYP3A4 inhibitors. 14. Patients requiring methotrexate and ibuprofen therapy. 15. Patients with active malignant tumors with an increased risk of bleeding, as determined by the investigator. 16. Pregnant or breastfeeding women, and those who have given birth within the past 90 days. 17. Premenopausal women not using adequate contraception. Adequate contraception requires at least two reliable methods, including one barrier method.