Can a simple standing test predict aneurysm risk?
NCT ID NCT05703893
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This observational study examines how the nervous system works in 139 adults with thoracic aortic aneurysms (a bulge in the chest's main artery). Participants lie down and then stand while their blood pressure and breathing are monitored non-invasively. The goal is to see if nerve function patterns can help predict who is at higher risk for serious complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better identify which patients with thoracic aortic aneurysms are at higher risk for complications.
- What could go wrong
- This is an early observational study, not a treatment trial. It may not lead to any changes in patient care or risk prediction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 139 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2021
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Primary care clinic, hospitals.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-65 years with syndromic and nonsyndromic TAA; * Signed informed consent; * Patients on regular pharmacological prophylaxis (with Losartan) or naïve patients with a first diagnosis Exclusion Criteria: * Acute and chronic inflammatory diseases such as: liver disease, chronic renal insufficiency (creatinine \> 1.5 mg/dl) and diseases affecting the thyroid system.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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IRCCS Policlinico San Donato
San Donato Milanese, Lombardy, 20097, Italy
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