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Hidden vitamin shortage: study reveals thiamine deficiency in hospitalized veterans

NCT ID NCT05480943

Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study looked at how often thiamine (vitamin B1) deficiency occurs in hospitalized veterans who do not abuse alcohol. Thiamine deficiency can cause symptoms like fatigue, confusion, and weakness, and may be more common in veterans due to food insecurity and chronic illness. Researchers measured blood thiamine levels in 206 veterans and also examined links to inflammation and diet. The goal was to better understand who is at risk and what blood level truly indicates a deficiency.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

206 people

The number who actually took part.

Started

Jul 2022

Finished

Dec 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Veterans who are admitted to the medicine service at the VA Sierra Nevada Healthcare System hospital in Reno, NV who do not use alcohol to excess. The Veterans will need to live within 75 miles of the medical center to facilitate return for follow up appointments.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * full admission to the hospital medical service (not on observation status) Exclusion Criteria: * excess alcohol intake as defined by the National Institute of Alcohol Abuse and Alcoholism * taking thiamine supplement * quadriplegic * lives more than 75 miles from the medical center * unable to demonstrate capacity to understand the study and provide informed consent

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Conditions

The condition(s) this trial relates to.

beriberi delirium polyneuropathy Thiamine Deficiency Wernicke encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thiamine deficiency Thiamine deficiency; sequelae

Contacts and locations

Locations

  • VA Sierra Nevada Health Care System, Reno, NV

    Reno, Nevada, 89502-0993, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.