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New oral combo shows promise for rare blood cancer

NCT ID NCT02844309

First seen Feb 16, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tested a three-drug oral regimen (thalidomide, cyclophosphamide, and dexamethasone) followed by maintenance therapy (thalidomide and prednisone) in 44 adults newly diagnosed with Waldenström macroglobulinemia, a rare blood cancer. The goal was to see how well the treatment controlled the disease. Participants had not received standard treatments like rituximab or bortezomib. The main measure was overall response rate, with progression-free survival also tracked.

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Contacts and locations

Locations

  • Shuhua Yi

    Tianjin, 300020, China

Conditions

Explore the condition pages connected to this study.