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Hope for tardive dyskinesia: tetrabenazine put to the test

NCT ID NCT01543321

First seen Nov 19, 2025 · Last updated May 21, 2026 · Updated 22 times

Summary

This study tested the drug tetrabenazine (Xenazine) in 54 adults with tardive dyskinesia, a condition causing uncontrollable movements after long-term antipsychotic use. The goal was to see if the drug could reduce these movements better than a placebo over 10 weeks. The approach was a double-blind, placebo-controlled trial to confirm if tetrabenazine is effective and safe for managing this often-irreversible side effect.

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Contacts and locations

Locations

  • AP-HM Hopital de la Timone

    Marseille, 13385, France

  • CH Aix en Provence

    Aix-en-Provence, 13100, France

  • CH des Charpennes

    Lyon, 69100, France

  • CHRU Lille

    Lille, 59037, France

  • CHRU de Nimes

    Nîmes, 30900, France

  • CHU Amiens

    Amiens, Picardie, 80000, France

  • CHU Bordeaux

    Bordeaux, 33076, France

  • CHU Caen

    Caen, 14033, France

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • CHU Limoges

    Limoges, 87042, France

  • CHU Montpellier

    Montpellier, 34295, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU Nice

    Nice, 06002, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Rouen

    Rouen, 76031, France

  • CHU Saint Antoine

    Paris, 75012, France

  • CHU Strasbourg

    Strasbourg, 67091, France

  • CHU Toulouse

    Toulouse, 31059, France

  • CHU de Rennes

    Rennes, 35033, France

Conditions

Explore the condition pages connected to this study.