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Could a 30-Minute face tickle ease ALS jaw pain?

NCT ID NCT07187388

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 36 times

Summary

This study tests whether a single 30-minute session of transcutaneous electrical nerve stimulation (TENS) on the face can reduce jaw and facial pain, improve jaw movement, and make chewing easier for people with ALS or PLS. Ten participants will receive the treatment during one clinic visit and report their pain and oral hygiene difficulty 24 hours later. It is a small, early-stage trial focused on symptom relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nova Southeastern University, David and Cathy Husman Neuroscience Institute

    RECRUITING

    Davie, Florida, 33314, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcutaneous Electrical Nerve Stimulation (TENS) device

What this could lead to

If it works, this could offer a simple, non-drug way to ease facial pain and improve jaw function and oral hygiene in people with ALS or PLS.

What could go wrong

This is a very small, early-stage trial with only 10 participants and a single treatment session. Results may not apply to everyone, and any pain relief may be temporary.

Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis Facial Pain motor neuron disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.