Gut check: new study probes how IBS drug changes your microbiome
NCT ID NCT05995899
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 19 times
Summary
This study looked at how tenapanor, a drug for irritable bowel syndrome with constipation (IBS-C), changes the bacteria and chemicals in the gut. Thirty-six adults took tenapanor twice daily for 8 weeks and provided stool samples. The goal was to understand the drug's effects on the gut's ecosystem, not to test if it works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Conditions
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