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Timing your meals and exercise may shrink fatty liver

NCT ID NCT05897073

Disease control Sponsor: Universidad de Granada Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether eating only during a set window each day (time-restricted eating) combined with supervised exercise can reduce fat in the liver and improve heart health in adults with obesity. 187 people took part. The goal was to see if the combination works better than either approach alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

187 people

The number who actually took part.

Started

May 2023

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 25-65 years. * Body mass index ≥28.0 and \<40.0 kg/m2. * Weight stability (within 5% of screening weight) for \>3 months prior to study entry. * Habitual eating window ≥11 hours. Exclusion Criteria: * History of a major adverse cardiovascular event, clinically significant kidney, endocrine, or neurological disease, bariatric surgery, HIV/AIDS, known inflammatory and/or rheumatologic disease, cancer, or other medical condition in which fasting or exercise is contraindicated. * Type 1 or Type 2 diabetes. * Major psychiatric disorders, eating disorders, sleep disorders, or alcohol abuse. * Regular use of medication or compounds that may affect study outcomes (e.g., antidiabetic, steroids, beta-blockers, antibiotics, prebiotics, probiotics and symbiotics). * Participating in a weight loss, a weight-management program or a supervised exercise program (more than 30 minutes three times per week, or 45 minutes twice a week, moderate/vigorous intensity). * Pregnancy and lactation or planned pregnancy (within the study period). * Caregiver for a dependent requiring frequent nocturnal care/sleep interruptions. Shift workers with variable hours (e.g., nocturnal). * Frequent travel over time zones during the study period. * Fear of needles and claustrophobia to magnetic resonance imaging (MRI). * Being unable to understand and to accept the instructions or the study objectives and protocol.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome fatty liver disease Intermittent Fasting metabolic syndrome X Motor Activity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiometabolic syndrome Exercise Hepatic steatosis Obesity Time restricted feeding

Contacts and locations

Locations

  • University of Granada

    Granada, Granada, 18011, Spain

  • University of Granada - Instituto Mixto Universitario Deporte y Salud

    Granada, Granada, 18011, Spain

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