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Heartbeat-Synced music therapy tested for MS pain relief

NCT ID NCT06800144

Symptom relief Sponsor: Istanbul Bilgi University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests whether listening to music or metronome sounds that match your heart rate can reduce chronic pain in people with multiple sclerosis. 45 participants will be split into three groups: one does motor imagery with a heartbeat-synced metronome, one listens to relaxing music synced to their heartbeat, and one continues usual care. All sessions are done at home via video calls over 8 weeks, and researchers will measure pain, fatigue, mood, sleep, and heart rate changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
heart rate-synchronized music therapy and motor imagery training
What this could lead to
If it works, this could offer a non-drug, home-based way to reduce chronic pain and improve mood, sleep, and quality of life for people with MS.
What could go wrong
This is a small, early-stage trial with only 45 participants, so results may not apply to everyone. The therapy is behavioral, so effects may be modest and require consistent participation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Mar 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being between the ages of 18-65. * Having a definite MS diagnosis according to the 2017 McDonald criteria. * Having a pain level of at least 3 and above on the numerical pain scale for at least 3 months. * Not having had an attack in the last 3 months. * Having a tablet or computer with an active internet connection that is suitable for videoconferencing. * Having a smartphone to which the heart rate monitor can be connected with the Bluetooth feature so that the heart rate synchronized music therapy training can be given. * Having sufficient smartphone/tablet or computer knowledge to participate in the study or having a relative who can help in this regard. * No change in the medications used for pain in the last 2 months. * Not receiving any additional treatment other than routine treatments. * Being able to read and understand Turkish. Exclusion Criteria: * Having a serious musculoskeletal, cardiovascular, pulmonary, metabolic or other disease that would prevent participation in the study. * Having a condition other than MS that can cause pain, such as cancer, diabetes, significant osteoarthritis or rheumatoid arthritis, based on laboratory or imaging findings * Having a psychiatric disease (such as active psychotic disorders, severe depression, anxiety disorders) that would prevent participation in the study and having a serious cognitive disorder determined by a physician that would prevent testing * Having a serious vision or hearing problem. * Being pregnant.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis (MS)

Contacts and locations

Locations

  • Istanbul Bilgi University

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.