New study tests online therapy and exercise for long COVID fatigue
NCT ID NCT06042751
First seen Jun 27, 2026 · Last updated Aug 18, 2026 · Updated 2 times
Summary
This study looks at whether online psychotherapy, a physical activity program, or a combination of both can reduce fatigue in people with Post-COVID syndrome. 195 adults with fatigue will be assigned to one of three groups for 3 months of treatment. The goal is to find which approach works best and for whom.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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195 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged over 18 and * diagnosed post-Covid-19 syndrome: (positive PCR or antibody test) and Fatigue Assessment Scale (FAS) ≥ 22 points Exclusion Criteria: * Current participation in another intervention study * Illnesses or functional disorders that potentially explain the fatigue symptoms otherwise * Any illness or impairment that the examining physician judges to preclude participation in a physical training intervention * Suicidality or severe mental illness (e.g. mania, acute phase of schizophrenia) that requires acute treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hannover Medical School
Hanover, Lower Saxony, 30625, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Will a digital boost keep Post-COVID recovery on track?
- Can tape or therapy soothe Post-COVID back pain?
- Brain fog after COVID: can two common drugs clear it?
- GP training may ease long COVID burden
- MRI study seeks clues to COVID brain fog