Hannover Medical School

This study tests a new treatment for progressive multifocal leukoencephalopathy (PML), a rare brain infection with no approved therapy. Researchers will give 23 patients donor immune cells that target the virus causing PML. The goal is to see if the treatment is safe, improves ne…

This study evaluates whether a blood test measuring polyreactive immunoglobulin G (pIgG) can more accurately diagnose autoimmune hepatitis (AIH) and distinguish it from other liver conditions. Researchers will collect blood samples from 400 adults undergoing liver biopsy for susp…

Researchers at Hannover Medical School are testing whether intermittent theta-burst stimulation (iTBS), a non-invasive brain stimulation technique, can reduce negative symptoms and improve thinking in people with schizophrenia. The trial enrolls 60 adults aged 18 to 65 with a sch…

This study tests whether a 3-month personalized exercise program can improve quality of life, fitness, and symptoms in people with myeloproliferative neoplasms (MPN), a group of rare blood cancers. About 80 participants will be randomly assigned to either start the exercise progr…

This study tests whether a robotic seal named PARO can reduce agitation, anxiety, and pain in patients recovering from visceral surgery. 300 adults having elective surgery will either use PARO or not, and their agitation levels will be tracked for three days. The goal is to find …

Researchers at Hannover Medical School are testing a new device called an auditory nerve implant (ANI) in five deaf adults. The implant stimulates the auditory nerve directly, and the study asks whether it can produce clear loudness and pitch percepts. Participants will have the …

This study tests whether a new video laryngoscope called i-scoop makes placing a breathing tube easier and safer than the standard C-Mac D-Blade device. Two hundred adults having surgery will be randomly assigned to one device while awake but sedated. Researchers will measure suc…

This study focuses on people with ME/CFS or Long COVID who are too sick to leave home. Researchers will provide monthly in-home medical visits and create personalized care plans. The goal is to see if this approach improves patients' health and eases the burden on their caregiver…

This registry follows 250 patients with decompensated liver cirrhosis who receive a TIPS procedure, a shunt placed in the liver to reduce pressure. Researchers will track survival, brain function, nutrition, and quality of life over one year. The goal is to identify which patient…

This study looks at how well people with alcohol-related liver cirrhosis understand health information and how confident they feel managing their condition. Researchers will survey 200 participants to measure these factors and track liver complications over time. The goal is to l…