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Brain zaps plus therapy: a new hope for children with cerebral palsy?

NCT ID NCT07746856

Disease control Sponsor: October 6 University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether adding a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to standard physiotherapy can improve hand function and quality of life in children with hemiparetic cerebral palsy. Sixty children aged 7 to 12 will be randomly assigned to receive either tDCS combined with functional task training or task training alone for one month. Researchers will measure grip strength, hand dexterity, muscle stiffness, and quality of life before and after treatment to see if the combination offers extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) combined with functional task training
What this could lead to
If effective, this combination could offer a non-invasive way to boost hand recovery and quality of life in children with cerebral palsy, potentially enhancing standard rehabilitation.
What could go wrong
The trial is small and early, and results may not apply to all children. tDCS is generally safe but may cause mild discomfort or skin irritation, and its benefits over standard therapy are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

7 to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 7 to 12 years old * Diagnosis of unilateral spastic hemiparetic cerebral palsy * Both sexes (male and female) * Able to understand and follow simple instructions * Able to maintain a sitting position for at least 60 minutes * Stable medication regimen for at least 3 months prior to study entry Exclusion Criteria: * Blindness, sickness, or language defects impairing patient cooperation * Epilepsy or abnormal electroencephalography (EEG) * Previous brain surgery * Skin irritation or dysfunction at electrode placement site * Metallic implants within the brain * Inability to consent or undergo tDCS therapy * Presence of cardiac abnormalities * Received botulinum toxin injections in the upper limb within the past 6 months

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Conditions

The condition(s) this trial relates to.

cerebral palsy cerebral palsy spastic hemiplegic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy

Contacts and locations

Locations

  • Out-patient Clinic, Faculty of Physical Therapy, October 6 University

    Giza, Giza Governorate, 123, Egypt

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