Brain zaps to zap vaping: new study tests tDCS for E-Cig addiction
NCT ID NCT06885606
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a non-invasive brain stimulation technique called tDCS can help people who vape nicotine daily to cut back. Forty adults aged 18-65 who vape regularly will receive either real or fake tDCS for 10 sessions over two weeks. Researchers will measure changes in vaping frequency and cravings at the end of treatment and again at 1 and 3 months later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The participant must meet all of the inclusion criteria to be eligible for this research study: 1. Be able to provide informed written consent 2. Stated willingness to comply with all study procedures 3. Age 18 - 65 years 4. Is a daily regular use of nicotine-containing e-cigarette for at least the past 6 months 5. Is willing to attend daily appointments for tDCS for two consecutive weeks (Monday through Friday) 6. Is not interested in or planning to quit vaping in the next 30 days. Exclusion Criteria: * An individual who meets any of the following criteria will be excluded from participation in this research study: 1. Substance use disorder (other than nicotine dependence) (M.I.N.I. SCID) (confirmed with urine drug screen) 2. Current regular use of tobacco cigarettes, nicotine replacement therapy or other medications for smoking cessation 3. Unstable psychiatric condition 4. Recent clinically significant head trauma\* 5. History of seizures and/or epilepsy\* 6. Pacemakers or implanted electrical devices such as cochlear implants\* 7. Metal embedded in the skull\* 8. Skin lesions, open wounds, bruising, or similar injuries on the scalp\*
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre for Addiction and Mental Health
RECRUITINGToronto, Ontario, M6J 1H4, Canada
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Other studies related to the condition(s) this trial covers.
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