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Shock therapy for stroke fatigue? new trial tests brain zaps

NCT ID NCT06149897

Symptom relief Sponsor: Hospital Clinic of Barcelona Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a gentle brain stimulation technique called tDCS, combined with health education and aerobic exercise, can help reduce fatigue in people who have had a stroke. 54 participants who had a first stroke within the past 45 days and reported significant fatigue took part. The goal was to see if this approach is feasible and effective for easing post-stroke tiredness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) device
What this could lead to
If it works, this could point toward a drug-free way to reduce post-stroke fatigue and improve daily life.
What could go wrong
This is a small, early feasibility study with no phase, so results may not be conclusive. The effect of tDCS on fatigue is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

54 people

The number who actually took part.

Started

Nov 2023

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * First stroke within 45 (+-7) days of the ischemic or hemorrhagic episode. * Ability to understand and execute simple instructions * Over 18 years. * Fatigue Scale of fatigue severity with a score greater than or equal to 24 Exclusion Criteria: * A score \> 2 on the modified Rankin Scale (mRS) before the stroke. * Patients with decompensated cardiorespiratory and/or psychiatric pathology. * Comorbidity causing disproportionate fatigue, such as long-term COVID. * Patients who are cancer survivors or who are undergoing cancer treatment. * Patients with a history of epilepsy or who are taking antiepileptic medication. * Patents with major depression.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

Contacts and locations

Locations

  • Hospital Clínic de Barcelona

    Barcelona, Spain, 08036, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.