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A gentle brain zap might boost hand skills in kids with cerebral palsy

NCT ID NCT04725019

Symptom relief Sponsor: Boston University Charles River Campus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study tests whether a mild electrical current applied to the scalp, called transcranial direct current stimulation (tDCS), can enhance motor learning in children with unilateral spastic cerebral palsy. Participants aged 6 to 17 will receive tDCS or a sham during five days of bimanual hand training. Researchers will measure changes in hand coordination and speed, as well as brain plasticity, to see if the stimulation amplifies the benefits of practice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS), a non-invasive brain stimulation device, combined with motor training
What this could lead to
If it works, this could point toward a way to help children with cerebral palsy improve hand coordination and movement speed more effectively.
What could go wrong
This is an early, small trial, and results may not apply to all children. tDCS is generally safe but may cause mild discomfort or tingling.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Mar 2023

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Children between 6-17 years old who have been diagnosed with cerebral palsy, with the following joint mobility: wrist extension 20º, metacarpophalangeal and proximal interphalangeal joints 10º. Ability to cooperate and follow simple directions. Exclusion Criteria: * Seizure beyond age 2, use of anti-seizure medication, history or family history of epilepsy, cranial metal implants, structural brain lesion, devices that may be affected by tDCS or TMS (pacemaker, medication pump, cochlear implant, implanted brain stimulator) * True positive response on the Transcranial Magnetic Stimulation and MRI Safety Screen * Current use of medications known to lower the seizure threshold * Previous episode of unprovoked neurocardiogenic syncope * Indwelling metal or incompatible medical devices * Centrally-acting medications including anti-seizure medications * Evidence of scalp disease or skin abnormalities * Current medical illness unrelated to CP * High motor ability in affected arm (i.e. no asymmetry in scores of hand function) * Severe spasticity * Lack of asymmetry in hand function * Orthopedic surgery in affected arm * Botulinum toxin therapy in either upper extremity during last 6 months, or planned during study period * Currently receiving intrathecal baclofen * History of broken arm (either arm) 1 year prior to study enrollment

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Conditions

The condition(s) this trial relates to.

cerebral palsy cerebral palsy spastic hemiplegic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy

More trials for these conditions

Other studies related to the condition(s) this trial covers.