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New transplant technique aims to cut deadly side effect in Half-Matched donors

NCT ID NCT05236764

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 31 times

Summary

This study tests a way to make stem cell transplants safer for people with blood cancers or immune disorders who don't have a fully matched donor. By removing certain immune cells from the donated cells, doctors hope to lower the risk of graft-versus-host disease, a serious complication. The approach uses a half-matched family donor and aims to let patients avoid long-term anti-rejection drugs. The trial is early-stage and includes both children and adults.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.