Brain injury study uses virtual reality to uncover hidden walking struggles
NCT ID NCT07230002
First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 2 times
Summary
This study looks at how people with moderate to severe traumatic brain injury (TBI) walk and navigate in complex, real-life-like virtual environments, such as streets with other people. Researchers want to understand the specific difficulties these individuals face during everyday walking tasks. The study involves 40 participants who are at least 3 months past their injury and can walk without help. No treatment is given; the goal is to gather knowledge to improve future rehabilitation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for Traumatic Brain Injury group : * 18 ≤ Age ≤ 55 years old * Male/female * Having suffered a first non-penetrating head injury * Moderate to severe severity with initial Glasgow Coma Scale score 5\<GCS\<13 * In the subacute or chronic phase (≥ 3 months at the date of the experiment, relative to the date of the injury) * Able to walk (10WMT speed ≥ 0.8 m/s, able to walk at least 20 m without technical or human assistance, PM ≥ 300 m) * Able to maintain dynamic balance while standing (TUG\<16s) * Able to answer simple questionnaires, according to the investigator's judgment * Having given their free, informed, expressed (written) consent * Registered with a social security system * Individuals under legal protection measures such as guardianship may be eligible Inclusion Criteria for healthy control group : * 18 ≤ Age ≤ 55 years old * Male/female * Able to walk (≥ 0.8 m/s, able to walk at least 20 m without technical or human assistance, PM ≥ 300 m) * Able to answer simple questionnaires, according to the investigator's judgment * Having given free, informed, expressed (written) consent * Registered with a social security system Exclusion Criteria specific to patients in the traumatic brain injury group : \- Person under legal protection (excluding guardianship) or unable to express consent Exclusion Criteria for both groups : * Severe patho-psychiatric care underway, which may impact the conduct of the protocol, at the investigator's discretion * Presence of neurological signs suggestive of a neurodegenerative disease responsible for gait disturbance (Parkinson's syndrome, Alzheimer's disease, etc.) * Individuals with musculoskeletal disorders that impact their locomotor abilities * Presence of uncontrolled epilepsy at the time of inclusion * Presence of visual impairments that make experimentation impossible, at the discretion of the investigator * Pregnant, parturient, or breastfeeding women * Participants in another ongoing research protocol involving human subjects Exclusion Criteria for healthy control group : * Presence of fatigue, trauma, or a condition affecting mobility, posture, balance, or walking * Persons deprived of their liberty by a judicial or administrative decision * Persons deprived of their liberty by judicial or administrative decision * Persons under legal protection (guardianship, curatorship, judicial protection) or unable to express their consent * Persons undergoing severe psychiatric treatment or admitted to a health or social care facility for purposes other than research.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fondation Saint Helier
RECRUITINGRennes, 35043, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a web program rebuild memory after brain injury?
- Why a simple fall can cause brain bleeding in older adults
- Bedside ultrasound could flag hidden brain injury decline
- Zapping the brain to restore lost vision
- Machine learning may forecast brain decline after head injury
- MRI tracer could expose hidden brain energy crisis after head injury