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Gene-Guided dosing may improve TB prevention

NCT ID NCT05413551

First seen Jan 05, 2026 · Last updated May 22, 2026 · Updated 22 times

Summary

This study tested whether adjusting the dose of a tuberculosis (TB) prevention drug based on a person's genetic makeup could improve treatment. Researchers gave 73 people at risk for TB a genetic test to guide their isoniazid dose. The goal was to see if this personalized approach leads to better drug levels in the blood, potentially making prevention safer and more effective.

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Contacts and locations

Locations

  • Federal University of Mato Grosso do Sul

    Campo Grande, Mato Grosso do Sul, Brazil

Conditions

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