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New score could help spot TB in starving children

NCT ID NCT04240990

First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 22 times

Summary

This study enrolled 603 severely malnourished children in Uganda and Zambia to develop a score that helps doctors decide whether to treat tuberculosis. Researchers tested children with chest X-rays, lab tests, and symptom checks. The goal is to create a simple, accurate tool to diagnose TB in this vulnerable group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arthur Davidson Children Hospital

    Ndola, Zambia

  • Lusaka University Teaching Hospital

    Lusaka, Zambia

  • Mulago National Referral Hospital

    Kampala, Uganda

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could give doctors a simple, reliable tool to diagnose TB earlier in severely malnourished children, potentially saving lives.

What could go wrong

This is an observational study that only develops a prediction score; it does not test a treatment. The score may not work well in other hospitals or countries.

Conditions

The condition(s) this trial relates to.

disease Malnutrition nutritional deficiency disease Severe Acute Malnutrition tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.