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Ear nerve zaps may unfreeze shoulders: new trial tests pain relief without drugs

NCT ID NCT07711353

Symptom relief Sponsor: Muhsin Doran Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether adding a gentle electrical stimulation to the ear (transcutaneous auricular vagus nerve stimulation, or taVNS) to standard physiotherapy can reduce pain, improve shoulder movement, and boost quality of life in adults with frozen shoulder (adhesive capsulitis). Forty participants aged 18 to 65 will receive 15 physiotherapy sessions over three weeks, with either active taVNS or a sham device. Researchers will measure changes in pain and disability before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous auricular vagus nerve stimulation (taVNS) added to standard physiotherapy
What this could lead to
If it works, this could offer a drug-free way to boost recovery from frozen shoulder by combining nerve stimulation with standard exercises.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The added benefit of taVNS over physiotherapy alone may be small or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years. * Clinical diagnosis of adhesive capsulitis confirmed by physical examination and, when clinically indicated, imaging. * Shoulder pain and limitation of shoulder range of motion for at least 3 months. * Provision of written informed consent. * General health status sufficient to participate in standard physiotherapy and active or sham transcutaneous auricular vagus nerve stimulation. * Ability to comply with the planned treatment sessions and outcome assessments. Exclusion Criteria: * Shoulder stiffness secondary to trauma, surgery, infection, or tumor. * Rotator cuff tear, advanced glenohumeral osteoarthritis, or inflammatory rheumatic disease. * Glucocorticoid injection into the affected shoulder within the previous 3 months. * Surgical intervention involving the affected shoulder within the previous 6 months. * Active infection or skin lesion in the shoulder region. * Cervical radiculopathy, brachial plexopathy, stroke, or another neurological disorder affecting the upper extremity. * Presence of a cardiac pacemaker or another implanted electronic device. * Pregnancy or breastfeeding. * Serious systemic disease or cognitive impairment that may prevent compliance with the study protocol. * Known intolerance or previous adverse reaction to transcutaneous electrical stimulation.

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Conditions

The condition(s) this trial relates to.

bursitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesive capsulitis of the shoulder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Liv hospital Vadistanbul

    RECRUITING

    Istanbul, Istanbul, 34381, Turkey (Türkiye)

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