Toothbrush bristle showdown: which shape cleans better without hurting gums?
NCT ID NCT07306026
First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 2 times
Summary
This study tests whether toothbrushes with tapered bristles are better at removing plaque and reducing gum bleeding than regular round bristles, without causing scratches. About 70 adults with gum disease will use one of two toothbrushes at home for 4 weeks. Researchers will check plaque, gum pocket depth, bleeding, and any gum damage.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must have read, understood and signed an informed consent prior to being entered into the study. * Must be 18 to 70 years of age, male or female. * Have at least 20 natural or restored teeth, not including implants. * Must have average Plaque Index of greater than 2 at screening. * Must have more than 20% of pockets with bleeding on probing at screening. * Agree not to have a dental prophylaxis or any other elective, non-emergency dental procedures any time during the study. * Agree to refrain from regular oral hygiene regimen for 24 hours and eating for 4 hours before the appointment in the study. * Agree to abstain from the use of any dental products other than those provided in the study. * Agree to comply with the conditions and schedule of the study. Exclusion Criteria: * Physical limitations or restrictions that might preclude normal tooth brushing. * Evidence of gross oral pathology * Periodontal probing pocket depths (PPD) ≥ 5mm. * Evidence of major soft tissue lesions or trauma at the baseline visit as determined by the examiner. * Chronic disease with concomitant oral manifestations * Subjects who are currently undergoing, or require, extensive dental work, orthodontic treatment or periodontal surgery, or orthodontic treatment in the preceding 3 months * Currently using bleaching trays * Eating disorders * Recent history of substance abuse * Smoking \>10 cigarettes/day * Participation in other clinical studies within 14 days of screening * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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SUNY Buffalo School of Dental Medicine
RECRUITINGBuffalo, New York, 14214, United States
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