Which pain block works best after C-Section? new trial aims to find out
NCT ID NCT04711096
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This trial compares two ways to manage pain after a cesarean section done under general anesthesia: an ultrasound-guided TAP block (injecting numbing medicine into the abdominal wall) versus injecting the same medicine directly into the surgical wound. Both methods are already used, but it is unclear which provides better pain relief and reduces the need for stronger opioid painkillers. The study includes 300 women aged 18–40 with a normal BMI, and will measure pain scores and opioid use over 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If one method proves better, it could become the standard for managing pain after cesarean sections, reducing opioid use and improving recovery.
- What could go wrong
- This is a single-center trial with 300 participants, so results may not apply to all hospitals or patients. Both methods are already used, so the difference may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
300 people
The number who actually took part.
- Started
-
Jan 2021
- Finished
-
Sep 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study subjects will randomly assigned to 3 equal groups (TAP group and infiltration group and Narcotics only group) of patients undergoing elective cesarean section under general anathesia in Ain Shams Maternity hospital
- Ages
-
18 to 40 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Patients undergoing elective cesarean section under general anathesia * Pfannenstiel Skin Incision * Age between 18 and 40 years old * BMI between 18 and 35 kg/m2 Exclusion Criteria: * • Patient refusal. * BMI\<18 kg/m2 or\>35 (require different dose of analgesia) * Height \<150 or \> 180 cm (require different dose of analgesia) * Patients with any neurological deficit due to neuropathy and pain score affection * Patients with bleeding disorders which may lead to hematoma * HTN (Vasculopathy which can lead to hematoma). * Cardiac disease ( Vasculopathy on anticoagulant which can lead to hematoma) * DM (decrease systemic and local immunity which can lead to abscess at injection site and due to neuropathy and pain score affection). * Liver disease (defective clotting factors). * A history of relevant drug allergy or Hypersensitivity to any of the drugs used in the study due to impair of proper follow up of pain postoperative * History of recent opioid exposure due to affection on pain score * Local skin infection due to abscess formation * Obstetric complications e.g placenta previa and rupture uterus due to extensive tissue damage and dissection
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Postoperative pain control are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams University Maternity Hospital
Cairo, 11865, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.