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Timing of pain block during Weight-Loss surgery may cut opioid use

NCT ID NCT04787367

Symptom relief Sponsor: Arthur Carlin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study looks at whether giving a nerve block (TAP block) early during laparoscopic sleeve gastrectomy reduces pain more than giving it later. About 200 adults having this weight-loss surgery will receive the same numbing medicine, but at different times. Researchers will compare pain scores and how much opioid painkiller patients need afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If early timing works better, it could improve pain control and reduce opioid use after weight-loss surgery.
What could go wrong
This is a single-center study with 200 participants, so results may not apply to all patients. Pain is subjective and other factors may influence outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Feb 2019

Finished

Jul 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Undergoing laparoscopic sleeve gastrectomy Exclusion Criteria: * Conversion to open procedure * Prior history of narcotic use (which will be defined as any narcotics used on a recreational basis or any narcotic used for pain relief without having had recent operation or injury) * Current narcotic use at time of surgery * Prolonged case time defined as \>1 standard deviation over average time

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Pain, postoperative

Contacts and locations

Locations

  • Henry Ford Macomb Hospital

    Clinton Township, Michigan, 48038, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.