Flomax may keep men from needing catheters after lung cancer surgery
NCT ID NCT05657990
First seen Jun 26, 2026 · Last updated Sep 10, 2026 · Updated 3 times
Summary
This study tests whether taking Tamsulosin (Flomax) for a week before surgery can help older men urinate normally after thoracic cancer surgery. About 46 men aged 55 and older will take the drug and have their bladder checked after surgery. The goal is to see if fewer men need catheters or other help to urinate.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Tamsulosin (Flomax)
- What this could lead to
- If it works, this could point toward a simple way to prevent urinary retention after chest cancer surgery, reducing the need for catheters.
- What could go wrong
- This is a very early, small feasibility study with only 46 men. It may not show a clear benefit, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 46 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males * ≥55 years old * Planned thoracic oncological surgical procedure of a video assisted oncological surgical procedure for suspected or confirmed cancer. * Surgery scheduled more than 7 days from the time of consent Exclusion Criteria: * Using Tamsulosin already * Known allergy to Tamsulosin or sulfa drugs * Current use of Boceprevir * Resting systolic blood pressure \<100 * Orthostatic hypotension of \>20mm Hg systolic and/or 10mm Hg diastolic pressure from sitting to standing (after 2 minutes of standing) as measured at the time of consent * Known history of hypotension * Known diagnosis of congestive heart failure (CHF) and valvular heart disease * History of prior prostate surgery (prostatectomy, trans-urethral resection)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jersey Shore University Medical Center
RECRUITINGNeptune City, New Jersey, 07753, United States
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Ocean University Medical Center
RECRUITINGBrick, New Jersey, 08724, United States
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Riverview Medical Center
RECRUITINGRed Bank, New Jersey, 07701, United States
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South Ocean University Medical Center
RECRUITINGManahawkin, New Jersey, 08050, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Prostate drug tested to stop urinary problems after rectal surgery
- New catheter design aims to make Self-Catheterization easier and more comfortable
- Can a precise prostate surgery predict better outcomes? a new study aims to find out.
- Bladder wash could cut infections and hospital visits for catheter users
- Prostate drug tested in women to prevent Post-Surgery urinary blockage
- Timing matters: study probes catheter use before prostate surgery