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Tamoxifen gel vs. pill: can a cream lower breast cancer risk?

NCT ID NCT04570956

First seen Jan 04, 2026 · Last updated Apr 29, 2026 · Updated 18 times

Summary

This study tested two forms of tamoxifen—a pill and a skin gel—against no treatment in women at high risk for breast cancer due to atypical hyperplasia or lobular carcinoma in situ. The goal was to see short-term changes in breast tissue. The study was stopped early and involved 65 women.

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Contacts and locations

Locations

  • MD Anderson Cancer center at Cooper

    Camden, New Jersey, 08103, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

Conditions

Explore the condition pages connected to this study.