Vaginal flora fix: could probiotics stop preterm birth?
NCT ID NCT05966649
First seen Feb 28, 2026 · Last updated Apr 29, 2026 · Updated 6 times
Summary
This study tests whether taking synbiotics (a mix of probiotics and prebiotics) early in pregnancy can help prevent preterm birth in women who have had a preterm birth before. About 402 pregnant women with a history of early delivery will take either synbiotics or a placebo daily from their first trimester. The goal is to see if the supplement can stabilize the vaginal microbiome and extend pregnancy to full term.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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AZ Groeninge
RECRUITINGKortrijk, 8500, Belgium
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AZ Maria Middelares
RECRUITINGGhent, West-Vlaanderen, 9000, Belgium
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AZ Sint-Jan
RECRUITINGBruges, West-Vlaanderen, 8300, Belgium
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AZ Sint-Lucas
RECRUITINGBruges, West-Vlaanderen, 8310, Belgium
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CHR Citadelle
RECRUITINGLiège, Liège, 4000, Belgium
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UZ Gent
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
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Universitaire Ziekenhuis Antwerpen
RECRUITINGEdegem, Antwerpen, 2650, Belgium
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Universitaire Ziekenhuizen Leuven
RECRUITINGLeuven, Limburg, 3000, Belgium
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Ziekenhuis Oost-Limburg
RECRUITINGGenk, Limburg, 3600, Belgium
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