Vaginal flora fix: could probiotics stop preterm birth?

NCT ID NCT05966649

First seen Feb 28, 2026 · Last updated Apr 29, 2026 · Updated 6 times

Summary

This study tests whether taking synbiotics (a mix of probiotics and prebiotics) early in pregnancy can help prevent preterm birth in women who have had a preterm birth before. About 402 pregnant women with a history of early delivery will take either synbiotics or a placebo daily from their first trimester. The goal is to see if the supplement can stabilize the vaginal microbiome and extend pregnancy to full term.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Groeninge

    RECRUITING

    Kortrijk, 8500, Belgium

    Contact

    Contact Phone: •••-•••-••••

  • AZ Maria Middelares

    RECRUITING

    Ghent, West-Vlaanderen, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AZ Sint-Jan

    RECRUITING

    Bruges, West-Vlaanderen, 8300, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • AZ Sint-Lucas

    RECRUITING

    Bruges, West-Vlaanderen, 8310, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHR Citadelle

    RECRUITING

    Liège, Liège, 4000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UZ Gent

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitaire Ziekenhuis Antwerpen

    RECRUITING

    Edegem, Antwerpen, 2650, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaire Ziekenhuizen Leuven

    RECRUITING

    Leuven, Limburg, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ziekenhuis Oost-Limburg

    RECRUITING

    Genk, Limburg, 3600, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.