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Drug combo aims to help smokers switch to vaping

NCT ID NCT05205811

First seen Feb 06, 2026 · Last updated May 26, 2026 · Updated 15 times

Summary

This study tested whether taking zonisamide and bupropion together helps smokers switch completely from regular cigarettes to e-cigarettes. 180 adult smokers who wanted to switch participated. They all received a JUUL e-cigarette and were randomly assigned to get the drug combination, bupropion alone, or a placebo for 7 weeks. The goal was to see if the drugs made it easier to stop smoking regular cigarettes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rose Research Center

    Charlotte, North Carolina, 28262, United States

  • Rose Research Center

    Raleigh, North Carolina, 27617, United States

Conditions

Explore the condition pages connected to this study.