Pill combo may help smokers ditch cigarettes for vapes

NCT ID NCT05205811

First seen Feb 06, 2026 · Last updated May 05, 2026 · Updated 13 times

Summary

This study tested whether two medications, zonisamide and bupropion, can help smokers switch completely to using an e-cigarette (JUUL) instead of regular cigarettes. 180 adult smokers who wanted to switch took part. They all received a JUUL and were randomly assigned to get either both medications, bupropion alone, or placebos for 7 weeks. The main goal was to see if they could stop smoking regular cigarettes entirely by the end of treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SMOKING CESSATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Rose Research Center

    Charlotte, North Carolina, 28262, United States

  • Rose Research Center

    Raleigh, North Carolina, 27617, United States

Conditions

Explore the condition pages connected to this study.