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Surgeons can do nerve blocks just as well as anesthesiologists for knee replacement pain

NCT ID NCT05601427

Symptom relief Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether surgeons can give a numbing shot (adductor canal block) during knee replacement surgery as effectively as an anesthesiologist does before surgery. 200 adults with knee osteoarthritis having same-day discharge were randomly assigned to one of the two methods. The goal was to see if the surgeon-performed block provides similar pain control and allows patients to go home safely on the same day.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Mar 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male and female patients aged 18 years or older 2. Primary TKA booked as SDD 3. Diagnosis of osteoarthritis Exclusion Criteria: 1. Inability or refusal to sign informed consent form 2. Non-English or French speaking, and no licensed translator, family member or substitute decision maker available. 3. Non-osteoarthritis primary diagnosis 4. Allergy to analgesic medications 5. Contraindication to spinal and/or regional anaesthesia 6. Any use of opioid pain medication within four weeks of the index procedure(13) 7. Pain catastrophizing scale score ≥16 (8, 9, 14) 8. History of cirrhosis 9. History renal insufficiency 10. History or sensory and/or motor neuropathy to the ipsilateral limb 11. Simultaneous, bilateral TKA 12. Non-TKA prosthesis 13. Scheduled for non-SDD TKA. 14. Preoperative varus/valgus of \>10 degrees. 15. Planned General Anaesthetic 16. Use of Intrathecal Morphine

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Knee arthritis Knee osteoarthritis Knee pain chronic

Contacts and locations

Locations

  • The Ottawa Hospital

    Ottawa, Ontario, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.