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New drug cocktail may spare kidney removal in High-Risk bladder cancer patients

NCT ID NCT06822010

First seen Nov 15, 2025 · Last updated Jun 17, 2026 · Updated 24 times

Summary

This study tests a two-drug combination (gemcitabine and Jelmyto) given in sequence to treat a high-risk type of upper urinary tract cancer. The goal is to destroy the tumor without removing the kidney, which is the usual treatment. About 28 adults with non-invasive, high-grade cancer will receive the drugs through a tube into the kidney. Researchers will check if the cancer disappears completely and monitor side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rutgers Cancer Institute

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

renal pelvis/ureter urothelial carcinoma urinary bladder cancer Urinary Bladder Neoplasms urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.