New study tests therapy to save homeless youth from suicide
NCT ID NCT05994612
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
Suicide is the leading cause of death among youth experiencing homelessness, and most don't get help. This study will test whether 10 sessions of Cognitive Therapy for Suicide Prevention (CTSP), delivered by outreach workers, can reduce suicidal thoughts, substance use, and depression in 300 homeless youth aged 15-24. Participants will be followed for 12 months to see if CTSP plus usual services works better than usual services alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Cognitive Therapy for Suicide Prevention (CTSP) – a 10-session behavioral therapy plus optional booster sessions
- What this could lead to
- If it works, this could provide an effective, community-delivered therapy to reduce suicidal thoughts and substance use in homeless youth.
- What could go wrong
- This is a relatively small, early-stage trial (300 participants) and the therapy may not outperform usual services. Results may not apply to all homeless youth.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 24 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 15-24 years * SSI-W score \> 4 or at least one suicide attempt in prior 12 months * Meets criteria for homelessness * At least four uses of alcohol/drugs in prior 30 days Exclusion Criteria: * Youth requires psychiatric hospitalization
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can 8 therapy sessions stop a second suicide attempt?
- Can a weekend retreat help prevent suicide in women veterans?
- Can a Co-Designed digital therapy help prevent suicide?
- Hand in hand: a Whole-School approach to preventing teen suicide
- Can a structured course help people at suicide risk build a personal safety plan?