Sweet solution may take the sting out of dental needles for children
NCT ID NCT07279285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a sugar-free sweet solution applied before a dental injection could lower pain in children aged 6 to 12. Fifty-four kids received either the sweet solution or plain water before their shot. Researchers measured pain using child reports, observer ratings, and heart rate changes. The goal is to find a simple, drug-free way to make dental visits less scary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sugar-free flavored sweet solution
- What this could lead to
- If it works, this could give dentists a simple, safe way to reduce injection pain for children without drugs.
- What could go wrong
- This is a small, completed trial with only 54 children. The effect may be small or not work for all kids, and results need to be confirmed in larger studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
54 people
The number who actually took part.
- Started
-
Jan 2026
- Finished
-
Apr 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
6 to 12 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Children who are 6-12 years of age. 2. Children classified as ASA1 according to the American Society of Anesthesiologists. 3. Children who have positive (Class III) or definitely positive (Class IV) behavior during preoperative behavioral assessments according to the Frankl Scale. 4. Children who required bilateral local anesthesia infiltration injections on primary or permanent teeth either in the maxilla or mandible for dental treatment (different types of restoration, stainless steel crowns, pulp therapy, and extractions). 5. Children with positive consent forms (signed and approved by their parents/ legal guardians) and attended the appointment. Exclusion Criteria: 1. Children who had a history of unpleasant experiences in dental settings. 2. Children who had a history of unpleasant experience with local anesthesia injection. 3. The presence of medically or developmentally compromising conditions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Lamis
Amman, Jordan
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