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Can a faint zap beat pain? new study puts nerve stimulation to the test

NCT ID NCT07170722

Symptom relief Sponsor: Umeå University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether very low-level electrical stimulation of nerves near the spine can reduce chronic pain more than a sham (inactive) device. Twenty adults who already have a nerve stimulator implant took part. Each person received both the real low-level stimulation and the sham for 5 days each, without knowing which was which. The goal was to see if the stimulation truly helps with pain, sleep, and mood.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Sep 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults, age 18 years or older * Implanted with a dorsal root ganglion (DRG) stimulator for chronic neuropathic pain * Have experienced at least 50% reduction in pain for 3 months or longer on standard DRG therapy * Stable pain medication regimen for at least 4 weeks before enrollment * Able and willing to complete electronic diaries and attend study visits Exclusion Criteria: * Active infection or wound complication at the stimulator implant site * Significant psychiatric illness (for example, uncontrolled depression or psychosis) * Planned surgery, device reprogramming, or medication changes during the study period * Currently pregnant or breastfeeding * Occurrence of any adverse event that meets predefined withdrawal criteria during the study (such as intolerable pain or device-related complications)

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome complex regional pain syndrome complex regional pain syndrome type 2 Failed Back Surgery Syndrome Low Back Pain neuralgia Pain, Postoperative Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Causalgia Chronic pain Complex regional pain syndromes (CRPS) Low back pain Neuropathic pain Pelvic pain

Contacts and locations

Locations

  • Neurokirurgiska kliniken. Neuromodulationsenheten

    Umeå, Västerbotten County, 90185, Sweden

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