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Scientists hunt for clues to chemo resistance in blood cancer

NCT ID NCT07385612

First seen Feb 04, 2026 · Last updated Jun 19, 2026 · Updated 20 times

Summary

This study collects blood and bone marrow samples from 80 people with B-cell non-Hodgkin lymphoma to explore why some cancers resist chemotherapy. Researchers will analyze the tumor and its environment, and develop lab models to test new treatments. The goal is to uncover resistance mechanisms and identify genes involved, which could lead to better therapies in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH de Saint-Nazaire

    Saint-Nazaire, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHD Vendée

    La Roche-sur-Yon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Nantes

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Poitiers

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could identify why some B-cell lymphomas resist chemotherapy, pointing toward new treatment targets.

What could go wrong

This is an observational study that collects samples, not a treatment trial. It may not directly lead to new therapies, and results may take years to translate into clinical use.

Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma mantle cell lymphoma neoplasm of mature B-cells

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.