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Can targeted leg exercises help stroke survivors walk better?
NCT ID NCT07659522
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether adding strength training for the tibialis anterior muscle (which lifts the foot) to proprioceptive (balance) exercises improves recovery in people who had a stroke at least six months ago. Participants will be assigned to six weeks of either balance exercises alone or balance exercises plus strength training. Researchers will measure changes in muscle strength, balance, walking, and daily function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Proprioceptive training with or without tibialis anterior strength training
- What this could lead to
- If successful, this could point toward a more effective rehabilitation program for chronic stroke survivors to improve balance, walking, and independence.
- What could go wrong
- This is a small, early-stage trial with 76 participants, so results may not apply to all stroke survivors. The exercises require physical ability and may not benefit those with severe impairments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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76 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Residual paresis in the lower extremity (Shahid et al., 2013). * Ability to sit unsupported for 30 seconds (Shahid et al., 2013). * Ability to follow 3 steps command (Shahid et al., 2013). * Least degree of the associated reaction (Shahid et al., 2013). * Survivor with stable C.V.S system (Shahid et al., 2013). * Survivor without fixed contracture of the lower extremity (Shahid et al., 2013). * Participants having a history of stroke within the prior 6 months or more (S. H. Chae et al., 2017). * Participants having ability to understand the directions from the researchers (those with a MMSE score of 24 or greater) (S. H. Chae et al., 2017). * Patients with grade 1 on modified Ashworth scale (Jan et al., 2019). Exclusion Criteria: * Presence of acute musculoskeletal symptoms (S. H. Chae et al., 2017). * Participants having inability to communicate, and those deemed unable to participate in the study by the researchers (S. H. Chae et al., 2017). * Serious cardiac condition (history of the CHF, documented serious and unstable cardiac arrhythmias (Shahid et al., 2013). * Hypertrophic cardiomyppathy, severe aortic stenosis, history of severe COPD. * Angina and dyspnea at rest or during ADL (Shahid et al., 2013).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Lahore Teaching Hospital
Lahore, 54590, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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