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Can targeted leg exercises help stroke survivors walk better?

NCT ID NCT07659522

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether adding strength training for the tibialis anterior muscle (which lifts the foot) to proprioceptive (balance) exercises improves recovery in people who had a stroke at least six months ago. Participants will be assigned to six weeks of either balance exercises alone or balance exercises plus strength training. Researchers will measure changes in muscle strength, balance, walking, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Proprioceptive training with or without tibialis anterior strength training
What this could lead to
If successful, this could point toward a more effective rehabilitation program for chronic stroke survivors to improve balance, walking, and independence.
What could go wrong
This is a small, early-stage trial with 76 participants, so results may not apply to all stroke survivors. The exercises require physical ability and may not benefit those with severe impairments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

76 people

The number who actually took part.

Started

Sep 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Residual paresis in the lower extremity (Shahid et al., 2013). * Ability to sit unsupported for 30 seconds (Shahid et al., 2013). * Ability to follow 3 steps command (Shahid et al., 2013). * Least degree of the associated reaction (Shahid et al., 2013). * Survivor with stable C.V.S system (Shahid et al., 2013). * Survivor without fixed contracture of the lower extremity (Shahid et al., 2013). * Participants having a history of stroke within the prior 6 months or more (S. H. Chae et al., 2017). * Participants having ability to understand the directions from the researchers (those with a MMSE score of 24 or greater) (S. H. Chae et al., 2017). * Patients with grade 1 on modified Ashworth scale (Jan et al., 2019). Exclusion Criteria: * Presence of acute musculoskeletal symptoms (S. H. Chae et al., 2017). * Participants having inability to communicate, and those deemed unable to participate in the study by the researchers (S. H. Chae et al., 2017). * Serious cardiac condition (history of the CHF, documented serious and unstable cardiac arrhythmias (Shahid et al., 2013). * Hypertrophic cardiomyppathy, severe aortic stenosis, history of severe COPD. * Angina and dyspnea at rest or during ADL (Shahid et al., 2013).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Lahore Teaching Hospital

    Lahore, 54590, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.