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New combo therapy aims to restore movement after stroke

NCT ID NCT07454954

Symptom relief Sponsor: The First Affiliated Hospital of Zhengzhou University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining two therapies—blood flow restriction training (using a cuff to partially restrict blood flow during exercise) and brain stimulation (rTMS)—can improve arm and hand function in people who have weakness on one side after a stroke. 69 adults will be split into three groups to compare standard rehab, rehab plus brain stimulation, and rehab plus both therapies. The goal is to see if the combo approach leads to better recovery of movement and daily activities over 4 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 69 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of stroke (ischemic or hemorrhagic) confirmed by CT or MRI, meeting the diagnostic criteria of the 4th National Cerebrovascular Disease Conference * First-ever stroke or recurrent stroke without residual dysfunction from prior events * Age 25-70 years, male or female * Stable vital signs, conscious, able to understand and follow therapist instructions * Brunnstrom stage III or above in both upper and lower limbs * Voluntary signed informed consent by patient or legal guardian Exclusion Criteria: * Presence of cardiac pacemaker or other metal implants * Deafness, severe cognitive impairment, history of psychiatric disorders * Shoulder subluxation * Extensive skin damage on affected limbs * Severe cardiac, hepatic, pulmonary, or renal insufficiency * Coagulation disorders * Post-stroke epilepsy * Malignancy * Pregnancy or lactation

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Conditions

The condition(s) this trial relates to.

hemiplegia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemiplegia Stroke

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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