Blood thinner vs. aspirin: which better prevents strokes after heart procedure?

NCT ID NCT02168829

Completed Disease control Sponsor: Ottawa Heart Institute Research Corporation Source: ClinicalTrials.gov ↗

Summary

This study compared two medication strategies to prevent strokes in people with atrial fibrillation (AFib) who had successfully undergone a procedure called catheter ablation to correct their irregular heartbeat. Researchers wanted to know if continuing with a stronger blood-thinning medication (rivaroxaban) was better than switching to daily aspirin alone at preventing strokes and other blood clot complications. The trial followed 1,284 participants for at least three years, using brain scans to check for silent strokes and monitoring for bleeding risks.

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Contacts and locations

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Locations

ASklepios

Hamburg, Germany
AZ Delta campus Wilgenstraat

Roeselare, Belgium
AZ Sint-Jan (Brugge)

Bruges, Belgium
Algemeen Stedelijk Ziekenhuis - campus Aalst

Aalst, Belgium
Arlon - Clinique du Sud-Luxembourg

Arlon, Belgium
Canberra Hospital

Canberra, Australian Capital Territory, 2605, Australia
Centre Hospitalier Universitaire de Liège

Liège, Belgium
Centre Hospitalier Universitaire de Sherbrooke

Sherbrooke, Quebec, Canada
Centre Hospitalier de L'Universite de Montreal (CHUM)

Montreal, Quebec, Canada
Elektrophysiologie GFO-Kliniken Bonn

Bonn, North Rhine-Westphalia, 53225, Germany
Europa Ziekenhuizen - ST-ELISABETH

Brussels, Belgium
Foothills Medical Centre

Calgary, Alberta, Canada
Galilee Medical Centre

Nahariya, 22100, Israel
Hamilton Health Sciences Centre

Hamilton, Ontario, Canada
Heart Rhythm Clinic

Nedlands, Western Australia, 6009, Australia
Herz- und Diabeteszentrum NRW Ruhr-Universitat Bochum

Bad Oeynhausen, North Rhine-Westphalia, 32545, Germany
Herzzentrum Leipzig

Leipzig, Leipzig, 04289, Germany
Herzzentrum der Universitat Koln

Cologne, North Rhine-Westphalia, 50937, Germany
Hôpital du Sacré-Coeur de Montreal

Montreal, Quebec, Canada
Imeldaziekenhuis

Bonheiden, Belgium
Institut Universitarie de Cardiologie et de Pneumologie de Quebec

Québec, Quebec, Canada
Jessa Ziekenhuis

Hasselt, Belgium
Kelowna Interior Health

Kelowna, Canada
Kerckhoff Klinik

Bad Nauheim, Hesse, 61231, Germany
Kingston General Hospital

Kingston, Ontario, Canada
Klinikum Coburg

Coburg, Bavaria, 96450, Germany
London Health Sciences Centre

London, Ontario, Canada
McGill University Health Centre

Montreal, Quebec, Canada
Melbourne Health

Melbourne, Victoria, 3050, Australia
Middelares Gent - AZ Maria Middelares

Ghent, Belgium
Montreal Health Institute

Montreal, Quebec, Canada
Onze Lieve Vrouw Ziekenhuis

Aalst, Belgium
Queen Elizabeth II Health Sciences Centre

Halifax, Nova Scotia, Canada
Royal Adelaide Hospital

Adelaide, South Australia, 5000, Australia
Royal Columbian/Fraser Clinical Trials

New Westminster, British Columbia, V3L 3W4, Canada
Scarborough Health Network- Rougevalley

Toronto, Ontario, Canada
Segeberger Liniken

Bad Segeberg, Schleswig-Holstein, 23795, Germany
Sherbrooke- Grandby site

Granby, Quebec, Canada
Sint-Jean - Kliniek Sint-Jan (Brussels)

Brussels, Belgium
Sir Run Run Shaw Hospital

Hangzhou, Zhejiang, China
Southlake Regional Health Centre

Newmarket, Ontario, Canada
St. Mary's General Hospital

Kitchener, Ontario, Canada
St. Michael's Hospital

Toronto, Ontario, Canada
St. Paul's Hospital

Vancouver, British Columbia, Canada
Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada
The Alfred Melbourne

Melbourne, Victoria, 3004, Australia
UKSH Lubeck

Lübeck, Schleswig-Holstein, 23538, Germany
Universitair Ziekenhuis Antwerpen (UZA)

Edegem, Belgium
Universitair Ziekenhuis Gent

Ghent, Belgium
Universitair Ziekenhuis Leuven, campus Gasthuisberg

Leuven, Belgium
Universitares Herzzentrum Hamburg

Hamburg, 20246, Germany
University of Ottawa Heart Institute

Ottawa, Ontario, K1Y 4W7, Canada
Victoria Cardiac Arrhythmia Trials Inc.

Victoria, British Columbia, Canada
ZNA Middelheim

Antwerp, Belgium
Ziekenhuis Oost-Limburg , campus St Jan

Lanaken, Belgium

Conditions

Explore the condition pages connected to this study.

ATRIAL FIBRILLATION STROKE