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3D scans reveal hidden Muscle's role in twisted neck disorder

NCT ID NCT05327985

Knowledge-focused Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how a small neck muscle called the obliquus capitis inferior (OCI) contributes to abnormal head rotation in cervical dystonia. Researchers used 3D CT scans to measure muscle function before and after botulinum toxin injections in 21 adults. The goal was to better understand which muscles are involved, which could help guide more precise treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better identify which muscles to inject with botulinum toxin for cervical dystonia, potentially improving treatment precision.
What could go wrong
This is a small, terminated observational study with only 21 participants. It does not test a new treatment, and results may not apply to all forms of cervical dystonia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

21 people

The number who actually took part.

Started

Sep 2024

Finished

Jul 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients suffering from predominantly rotatory focal cervical dystonia will be identified directly by investigators at the Fondation A. de Rothschild Hospital during abnormal movement consultations or during specialized rehabilitation sessions.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients between the ages of 18 and 70 * Presenting with a diagnosed focal CD with predominantly rotational by a neurologist specialized in abnormal movements * Receiving botulinum toxin injection at OIC level as part of his treatment * Express consent to participate in the study * Member of or beneficiary of a social security scheme Exclusion Criteria: * Mobile DC (scrapie and/or myoclonic) that cannot be controlled the recording time by the CBCT system * Having already benefited from an injection of BoNT as part of their DC in the last three months * Inability to sit still * Neurological condition other than DC (parkinsonian syndrome typical or atypical, others.) * Severe neck pain * Known or suspected trauma or pathology of the cervical spine, other than DC, having required treatment in the last 6 month * Same old surgery of the cervical spine * Patient benefiting from a legal protection measure * Pregnant or breastfeeding women (a urine pregnancy test will be carried out in women under 50)

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Conditions

The condition(s) this trial relates to.

cervical dystonia Torticollis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical dystonia

Contacts and locations

Locations

  • Hopital Fondation Adolphe de Rothschild

    Paris, 75019, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.