Could a simple steroid injection cut opioid use after knee surgery?
NCT ID NCT07151417
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 35 times
Summary
This study compares two types of steroid injections added to standard pain control during total knee replacement. The goal is to see which option reduces pain, limits opioid use, and improves knee movement. About 240 adults with severe knee arthritis will be randomly assigned to receive either standard injection alone, standard plus a traditional steroid, or standard plus an extended-release steroid. Researchers will track pain, medication use, and recovery for up to a year.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889, United States
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