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Which steroid works best for jaw surgery recovery? new study aims to find out

NCT ID NCT07208799

Symptom relief Sponsor: Nishtar Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common steroids, dexamethasone and methylprednisolone, to see which one better reduces swelling and pain after surgery for a broken lower jaw. About 72 adults aged 18 to 40 with a recent, isolated jaw fracture will receive one of the two drugs during surgery. Researchers will measure facial swelling and pain levels at 24 and 72 hours after the operation to determine the more effective option.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 18 to 40. 2. Both Gender. 3. Fracture less than a week old. 4. Isolated mandibular parasymphysis fractures. Exclusion Criteria: * 1\. Immunocompromised patients (due to increased risk of infection and complications). 2\. Patients experiencing acute pain from conditions such as pulpitis, abscesses, or other acute infections (to ensure that acute pain does not confound the study results). 3\. Patients reporting hypersensitivity to steroids (to avoid adverse reactions). 4\. Patients taking or requiring prophylactic antibiotics or anti-inflammatory drugs before surgery (to prevent confounding effects on study outcomes). 5\. Patients with a history of systemic steroid administration for 15 days (as this could affect the study's outcomes). 6\. Patients with chronic pain problems or mental disorders (to maintain consistency in response to treatment). 7\. Patients with comminuted fractures (to maintain consistency in fracture type). 8\. Pregnant or lactating women (to avoid potential risks to the fetus and nursing infant). 9\. Smokers who smoke at least 10 cigarettes per day for 2 years (to minimize the impact of smoking on healing and recovery). ria:

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Conditions

The condition(s) this trial relates to.

agnosia Edema jaw fracture Mandibular Fractures Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Corticosteroid injection Edema face Mandible fracture Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nishtar Institute of Dentistry Multan

    RECRUITING

    Multan, Punjab Province, 60000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.