Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Nasal drops from stem cells aim to heal stroke damage

NCT ID NCT07232563

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests whether nasal drops containing tiny particles from umbilical cord stem cells are safe for people who had an ischemic stroke. Nine patients will receive the drops four times over two weeks, alongside standard care. The main goal is to check for serious side effects, not yet to prove the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
stem cell vesicle nasal drops (hUC-MSC-sEV-001)
What this could lead to
If safe and effective, this could point toward a new way to help stroke patients recover without surgery or strong drugs.
What could go wrong
This is a very early, tiny safety trial with only 9 people. It may not show any benefit, and side effects or lack of effect are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 9 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Ischemic Stroke * Age 18-70 years, no gender restriction * Confirmed anterior circulation occlusion by CTA or MR angiography (MRA) * Pre-stroke mRS score of 0-1 * Post-stroke ASPECTS score \>= 6 * Pre-enrollment NIHSS score\>= 6 * Within 24 hours to 14 days of stroke onset * Patients who have not received thrombolysis or endovascular treatment * No significant liver or kidney dysfunction: ALT and AST\<= 2.5 times the upper limit of normal, serum creatinine and blood urea nitrogen \<= 1.25 times the upper limit of normal * No significant cardiac dysfunction * The subject or legal representative can sign the informed consent form and comply with the requirements of the study for administration and follow-up. Exclusion criteria: * Intracranial hemorrhagic conditions observed on cranial CT: hemorrhagic stroke, epidural hematoma, subdural hematoma, intraventricular hemorrhage, subarachnoid hemorrhage, or hemorrhagic transformation, etc. * Known severe allergy to contrast agents (excluding mild rash-type allergies) * Known bleeding tendencies (including but not limited to): platelet count \< 100×10\^9/L; received heparin treatment within 48 hours with aPTT \>= 35s; currently taking warfarin with INR \> 1.7 * Patients with brain tumors, or a history of epilepsy and severe head trauma * Patients with other systemic malignancies * Patients with other serious systemic diseases such as immunodeficiency, coagulation disorders, etc. * Patients with Alzheimer's disease, Parkinson's disease, or other neurodegenerative diseases that prevent them from completing follow-up * Patients with severe local infection, systemic infection, immunodeficiency, or those currently taking immunosuppressants * Patients who are positive for hepatitis B surface antigen or currently suffering from other infectious diseases * Patients who have allergic reactions to the drug used in this study or similar drugs * Patients with known allergic constitution * Patients with nasal structural abnormalities or lesions * Patients with cerebrospinal fluid rhinorrhea * Patients who have participated in other clinical trials within the past 3 months * Unwilling or unable to comply with the procedures specified in the protocol * Pregnant or breastfeeding women, or women of childbearing potential who are unwilling or unable to use appropriate contraceptive measures * Patients clearly lacking the compliance to complete the clinical trial, such as those suffering from uncontrolled mental illness * Other situations deemed unsuitable for enrollment by the researchers

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Ischemic stroke are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • 253 Gongye Blvd Middle, Guangzhou, Guangdong, China 510280

    Guangzhou, Guangdong, 510000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.