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Half-Matched stem cell transplant offers hope for severe sickle cell disease

NCT ID NCT03121001

First seen Jan 26, 2026 · Last updated May 20, 2026 · Updated 17 times

Summary

This study tests a stem cell transplant from a half-matched family donor for people with severe sickle cell disease. Participants receive low-dose radiation and chemotherapy before the transplant to help the new cells take hold. The main goal is to see if the donor cells successfully engraft by day 60, which could reduce or eliminate sickle cell complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.