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Tailored transplants aim to beat inherited blood cancers

NCT ID NCT07524530

First seen Apr 18, 2026 · Last updated May 24, 2026 · Updated 7 times

Summary

This study tests a stem cell transplant approach for people with blood cancers caused by an inherited RUNX1 gene mutation. The goal is to see if customizing chemotherapy and supportive care doses for each patient improves disease-free survival compared to standard transplant outcomes. The study involves 98 participants aged 4 to 70, plus donors and healthy volunteers, with follow-up for 3 years after transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.