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New stem cell method aims to protect kids with rare immune disease

NCT ID NCT02737384

First seen Apr 09, 2026 · Last updated Jun 18, 2026 · Updated 13 times

Summary

This study tested a way to improve stem cell transplants for children with combined immunodeficiency (CID), a condition where the immune system doesn't work properly. The approach removed certain naive cells from the donor stem cells to try to prevent graft-versus-host disease (a serious complication) while keeping the donor's memory T cells to fight infections. Only 4 children were enrolled before the study ended early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, Paris, 75015, France

Conditions

The condition(s) this trial relates to.

combined immunodeficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.