Could stem cells help paralyzed patients move again?
NCT ID NCT04064957
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a stem cell treatment for people with long-term spinal cord injuries. It involved three patients who received their own fat-derived stem cells through an IV. The goal was to see if the treatment could safely restore nerve signals and improve sensation or movement.
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Study facts
What this study's own registry entry says, in plain language.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
HBSCI02: Inclusion Criteria: 1. Adult individual 18 yr. of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of a non-penetrating traumatic SCI to the cervical spine 4. Patient and Caregiver agree to use Care Connect app or web version of VirTrial platform for virtual visits. Exclusion Criteria: 1. Prior history of: 1. Recent or ongoing infection, 2. Clinically significant cardiovascular, lung, renal, hepatic, or endocrine disease, 3. Neurodegenerative disorders, 4. Cancer, 5. Immunosuppression as defined by WBC \< 3, 000 cells/ml at baseline screening, 6. Chemical or ETOH dependency, 2. Having a contraindication to MRI scans 3. Other acute or chronic medical conditions that, in the opinion of the investigator, may increase the risks associated with study participation or HB-adMSC administration 4. Participation in other interventional research studies. 5. Unwillingness to return for follow-up visits HBSCI04: Inclusion Criteria: 1. Adult individual 18 years of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of Spinal Cord Injury. 4. Subject has mesenchymal stem cells banked at Hope Biosciences. 5. The patient accepts to receive treatment and to comply with follow-up visits. Exclusion Criteria: 1. Clinically significant, uncontrolled cardiovascular, lung, renal, hepatic, or endocrine disease or any other acute or chronic medical condition that, in the opinion of the investigator may increase the risks associated with study participation. 2. Active Alcohol or Drug addiction. 3. Participation in concurrent interventional research studies during this study. 4. Severe organ failure (heart, kidney or liver) confirmed by additional tests or medical history. 5. Unwillingness to return for follow-up visits. HBSCI05: Inclusion Criteria: 1. Adult individual 18 years of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of Spinal Cord Injury. 4. Subject has mesenchymal stem cells banked at Hope Biosciences. 5. The patient accepts to receive treatment and to comply with follow-up visits. Exclusion Criteria: 1. Clinically significant, uncontrolled cardiovascular, lung, renal, hepatic, or endocrine disease or any other acute or chronic medical condition that, in the opinion of the investigator may increase the risks associated with study participation. 2. Active Alcohol or Drug addiction. 3. Participation in concurrent interventional research studies during this study. 4. Severe organ failure (heart, kidney or liver) confirmed by additional tests or medical history. 5. Unwillingness to return for follow-up visits.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hope Biosciences Stem Cell Research Foundation
Sugar Land, Texas, 77474, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Pure oxygen tested as a switch for dormant nerves after spinal cord injury
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