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Could stem cells help paralyzed patients move again?

NCT ID NCT04064957

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended) This study
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a stem cell treatment for people with long-term spinal cord injuries. It involved three patients who received their own fat-derived stem cells through an IV. The goal was to see if the treatment could safely restore nerve signals and improve sensation or movement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

HBSCI02: Inclusion Criteria: 1. Adult individual 18 yr. of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of a non-penetrating traumatic SCI to the cervical spine 4. Patient and Caregiver agree to use Care Connect app or web version of VirTrial platform for virtual visits. Exclusion Criteria: 1. Prior history of: 1. Recent or ongoing infection, 2. Clinically significant cardiovascular, lung, renal, hepatic, or endocrine disease, 3. Neurodegenerative disorders, 4. Cancer, 5. Immunosuppression as defined by WBC \< 3, 000 cells/ml at baseline screening, 6. Chemical or ETOH dependency, 2. Having a contraindication to MRI scans 3. Other acute or chronic medical conditions that, in the opinion of the investigator, may increase the risks associated with study participation or HB-adMSC administration 4. Participation in other interventional research studies. 5. Unwillingness to return for follow-up visits HBSCI04: Inclusion Criteria: 1. Adult individual 18 years of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of Spinal Cord Injury. 4. Subject has mesenchymal stem cells banked at Hope Biosciences. 5. The patient accepts to receive treatment and to comply with follow-up visits. Exclusion Criteria: 1. Clinically significant, uncontrolled cardiovascular, lung, renal, hepatic, or endocrine disease or any other acute or chronic medical condition that, in the opinion of the investigator may increase the risks associated with study participation. 2. Active Alcohol or Drug addiction. 3. Participation in concurrent interventional research studies during this study. 4. Severe organ failure (heart, kidney or liver) confirmed by additional tests or medical history. 5. Unwillingness to return for follow-up visits. HBSCI05: Inclusion Criteria: 1. Adult individual 18 years of age or older. 2. Cognitively intact and capable of giving informed consent. 3. Clinical diagnosis of Spinal Cord Injury. 4. Subject has mesenchymal stem cells banked at Hope Biosciences. 5. The patient accepts to receive treatment and to comply with follow-up visits. Exclusion Criteria: 1. Clinically significant, uncontrolled cardiovascular, lung, renal, hepatic, or endocrine disease or any other acute or chronic medical condition that, in the opinion of the investigator may increase the risks associated with study participation. 2. Active Alcohol or Drug addiction. 3. Participation in concurrent interventional research studies during this study. 4. Severe organ failure (heart, kidney or liver) confirmed by additional tests or medical history. 5. Unwillingness to return for follow-up visits.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hope Biosciences Stem Cell Research Foundation

    Sugar Land, Texas, 77474, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.