Statins vs. smoke: can a pill protect your heart and brain?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Good general health and, if aged 45 year or more, low to intermediate (\<10%) atherosclerotic cardiovascular disease (ASCVD) risk category, based on clinical data measured within 12 months prior to enrolment. Exclusion Criteria: * History of severe chronic lung diseases such as chronic obstructive pulmonary disease or asthma as determined by participants' care providers. * History of chest pain, irregular heartbeats, heart failure, heart attack, heart pacemaker or coronary bypass surgery. * High cardiovascular risk (\>10%) category on the ASCVD risk calculator or judged to be at high risk by study cardiologist, for those aged 45 years or older. * History of stroke, dementia or other neurological condition * Untreated high blood pressure (≥ 140 systolic, ≥ 90 diastolic) * History of autoimmune or inflammatory rheumatic disease (e.g., rheumatoid arthritis, systemic lupus erythematosus, spondyloarthritis). Osteoarthritis alone is not an exclusion. * History of immunodeficiency * Diabetes (any type) * Current medications: Long term medications that interact with atorvastatin (such as verapamil, digoxin and warfarin); Medications that affect heart rate variability including beta-blockers (such as atenolol, metoprolol, propranolol, and acebutolol), tricyclic antidepressants and selective serotonin reuptake inhibitors (such as amitriptyline, sertraline, fluoxetine or citalopram), or medications with anti-cholinergic action (such as promethazine or prochlorperazine); stimulant medications, such as those prescribed for ADHD (such as methylphenidate, dexamphetamine, lisdexamfetamine); anti-inflammatory, immunosuppressive or immune modulating medications including systemic corticosteroids (such as prednisolone, dexamethasone) and non-steroidal anti-inflammatory drugs (NSAIDS) (such as ibuprofen, naproxen or diclofenac) * Currently smoking, or have smoked: more than one pack of cigarettes in the past year, or have smoked more than 100 packs of cigarettes in their lifetime * Currently vaping or have vaped: more than 200 puffs in the last year, more than 20,000 puffs in their lifetime * Currently pregnant, attempting to become pregnant or breastfeeding * History of skin allergy to tape or electrodes * Inability to travel to the study site