Heart plaque showdown: combo pill vs. super statin

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult men and women over the age of 18 years. * Patients with coronary artery disease undergoing a coronary intervention procedure using intravascular imaging. * At least one major native coronary artery ("target vessel") meeting all the following criteria for intracoronary imaging immediately following a qualifying PCI procedure: * Angiographic evidence of coronary artery stenosis ≥30% by angiographic visual estimation. * Target vessel is accessible to the imaging catheter and suitable for intracoronary imaging in the proximal 50 mm segment. * Target vessel is not a bypass graft (aortic or arterial) or a bypassed graft vessel. * Target vessel has not undergone PCI within the target segment. * Target vessel is not a candidate for PCI at the time of the procedure or for 6 months thereafter (per investigator's judgment). * Patients who have provided written informed consent to participate in the study. Exclusion Criteria: * Left main stem lesion: Left main coronary artery stenosis ≥50% by coronary angiographic visual estimation. * History of coronary artery bypass graft surgery (CABG). * Unstable clinical condition (hemodynamic or electrical instability). * Severe coronary artery calcification or tortuosity interfering with IVUS, NIRS, or evaluation. * Uncontrolled cardiac arrhythmia (recurrent and symptomatic ventricular tachycardia or atrial fibrillation with rapid ventricular response) not controlled by medication within 3 months prior to screening. * Active liver disease or liver dysfunction. * Severe renal dysfunction (eGFR \<30 mL/min/1.73m²) * Known allergy to contrast media, heparin, aspirin, ticagrelor, or prasugrel. * Active infection or major hematologic, metabolic, or endocrine dysfunction as determined by the investigator. * Planned surgery within 12 months. * Currently enrolled in another investigational device or drug study. * Estimated life expectancy of less than 2 years. * Women of childbearing potential (under 50 years of age) who: * Had their last menstrual period within the last 12 months. * Have not had tubal ligation, oophorectomy, or hysterectomy.